BCSE Practice Exam 2025 – Complete Study Resource

The condition characterized by bullae and erosions is Pemphigus. This autoimmune disease involves the formation of fluid-filled blisters (bullae) on the skin and mucous membranes due to the loss of adhesion between skin cells. This occurs because the immune system mistakenly produces antibodies against desmosomes, which are structures that help cells stick to each other. As a result, the skin becomes fragile, leading to the development of erosions when the blisters rupture.

Pemphigus has different forms, with Pemphigus vulgaris being the most common. The blisters in this condition are painful and can easily burst, leading to open sores that can be susceptible to infection. The presence of these bullae and erosions is a key clinical feature that differentiates Pemphigus from other conditions associated with hypersensitivity.

In contrast, other conditions listed, such as Urticaria, Pemphigoid, and Atopic dermatitis, do not primarily manifest with bullae and erosions. Urticaria is characterized by raised, itchy welts on the skin but does not typically involve blister formation. Pemphigoid, while it also involves blistering, generally presents with tense blisters that may not erode as easily as those seen in